SAMUEL J. TAUB, M.D.; ELI RUBENS, M.D.
Dunbar, in 1905, was the first to attempt pollen desensitization against hay fever. He injected horses with crude pollen, then bled the animals and used the serum on hay fever patients. It is very obvious that this treatment was unsuccessful because of horse serum reactions, and the method soon fell into bad repute.
Noon, in 1911, was the first to place desensitization on a scientific basis by preparing an aqueous extract of timothy pollen. This work was further elaborated by Freeman, Koessler, Scheppegrell and Clowes. Glycero-saline extracts are still claimed to be the most stable, but when used in 50
TAUB SJ, RUBENS E. POLLEN IN OIL: A PRELIMINARY REPORT ON A NEW, SLOWLY ABSORBED MEDIUM FOR USE IN HAY FEVER TREATMENT1. Ann Intern Med. ;17:642–644. doi: 10.7326/0003-4819-17-4-642
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Published: Ann Intern Med. 1942;17(4):642-644.
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