LYNN T. HALL, M.D., F.A.C.P.; EDWARD THOMPSON, M.D.; RAYMOND J. WYRENS, M.D.; ALBERT M. HARRIS, M.D.; VIOLET WILDER, PH.D.
The efficacy of the sulfonamide drugs in the treatment of many infections is generally accepted. The Council on Pharmacy and Chemistry has listed certain sulfonamides, stating their action, use, toxicity, and general status. It must be emphasized, however, that these chemicals are still relatively new and, therefore, require further experimental study in some phases of their behavior. At present in the United States, oral or intravenous administration is favored, although in England1, 2 and Canada3 the intramuscular route is also used. We have studied the rapidity of absorption and secretion of the sulfonamide drugs, the degree of acetylation, and toxic
HALL LT, THOMPSON E, WYRENS RJ, HARRIS AM, WILDER V. PARENTERAL USE OF THE SULFONAMIDES: A CLINICAL AND EXPERIMENTAL STUDY1. Ann Intern Med. ;17:835–841. doi: 10.7326/0003-4819-17-5-835
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Published: Ann Intern Med. 1942;17(5):835-841.
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