WM. DEB. MACNIDER, F.A.C.P.
Fixity of any order, even fixity of purpose, tends to bind and render inelastic the structure or the individual in which such a property develops. It is a quality which is inimicable to adaptation, and tissues or organisms without this quality of elasticity, of variability, have difficulty in meeting the exigencies of life which is made up of periods of adequate adaptation, never perfect, and periods of inadequate adaptation which may be of such a specialized nature as to produce the symptoms and later show the signs of disease.
Since 1907 the investigations in this laboratory have not been so
MACNIDER WD. A CONSIDERATION OF THE FACTOR OF CHANGE IN THE ANIMAL ORGANISM1. Ann Intern Med. ;17:989–994. doi: 10.7326/0003-4819-17-6-989
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Published: Ann Intern Med. 1942;17(6):989-994.
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