L. E. CURTIS, M.D.; A. E. FELLER, M.D.
Hyperparathyroidism1, 2, 3 is usually due to an adenoma of one or more of the parathyroid glands, but occasionally it may be due to diffuse hypertrophy (hyperplasia?) 2 of all parathyroid tissue.4, 5 The adenomata6 may be composed of one dominant cell type or of a mixture of cell types, but the hypertrophic glands are uniformly composed of large cells with clear cytoplasm, the so-called large 3 "wasserhelle" cells. The distinction, however, is purely on the basis of the anatomical alterations in the parathyroid glands since the resultant disease is similar. Renal complications are common.7 For example, in a survey
CURTIS LE, FELLER AE. HYPERPARATHYROIDISM WITH CALCINOSIS AND SECONDARY TO RENAL DISEASE; REPORT OF A PROBABLE CASE1. Ann Intern Med. ;17:1005–1014. doi: 10.7326/0003-4819-17-6-1005
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Published: Ann Intern Med. 1942;17(6):1005-1014.
Endocrine and Metabolism, Nephrology, Parathyroid Disorders.
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