SAMUEL M. FEINBERG, M.D., F.A.C.P.; HOWARD L. ALT, M.D.; RICHARD H. YOUNG, M.D., F.A.C.P.
The last two or three decades have witnessed tremendous and far-reaching advances in therapeutics, in many instances specific in character. This has been particularly true in the case of highly potent injectable substances such as immune sera, hormones, vitamins, and such specific factors as the antianemic liver fraction. With the older types of materials allergic reactions such as asthma, urticaria or serum sickness were obtained and were not unexpected, since they contained a considerable quantity of the animal proteins which were regarded as an essential feature of the mechanism of the reaction. Later, it was shown that even such a
FEINBERG SM, ALT HL, YOUNG RH. ALLERGY TO INJECTABLE LIVER EXTRACTS; CLINICAL AND IMMUNOLOGICAL OBSERVATIONS1. Ann Intern Med. ;18:311–322. doi: 10.7326/0003-4819-18-3-311
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Published: Ann Intern Med. 1943;18(3):311-322.
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