W. H. B.
The relation of vitamin deficiency to liver disease may be approached from two angles: (1) vitamin deficiency as an etiologic factor in the production of liver disease; (2) the rôle of preëxisting liver disease in the development of certain vitamin deficiency states.
An abundance of experimental evidence attests to the etiologic rôle of vitamin deficiency in the production of liver disease. MacLean and Best1 in 1934 reported that fat was deposited in the livers of rats kept on a high-fat intake and that this fatty deposition could be prevented by giving adequate choline (now generally regarded as a member of
B. WH. VITAMIN DEFICIENCY AND LIVER DISEASE. Ann Intern Med. ;18:410–413. doi: 10.7326/0003-4819-18-3-410
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Published: Ann Intern Med. 1943;18(3):410-413.
Gastroenterology/Hepatology, Liver Disease.
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