KURT H. ESSER, M.D.; KURT BERLINER, M.D.
Measurements of the velocity of blood flow, repeated at intervals on the same patient, are sometimes used to evaluate the treatment of congestive heart failure. It is obvious that such serial tests can be of value only if their results chiefly reflect changes in the degree of heart failure and are not materially influenced by other factors. That such extracardiac factors are operative has recently been proved by Lilienfeld and Berliner1 who used alpha lobeline hydrochloride as an agent and found wide "spontaneous" variations in the results of duplicate measurements. The present study was undertaken to determine whether duplicate measurements
ESSER KH, BERLINER K. DUPLICATE MEASUREMENTS OF CIRCULATION TIME MADE WITH THE SACCHARIN METHOD1. Ann Intern Med. 1943;19:64–69. doi: 10.7326/0003-4819-19-1-64
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Published: Ann Intern Med. 1943;19(1):64-69.
Cardiology, Hospital Medicine.
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