P. A. GRAY, M.D., F.A.C.P.
The clinical features of hemochromatosis as described in Sheldon's1 excellent monograph include (1) a predominant occurrence between 35 and 60 years of age, (2) a predilection for the male sex, (3) a familial background, (4) a short life expectancy (18½ months), and (5) a diagnostic triad of symptoms: pigmentation of the skin, diabetes mellitus, and cirrhosis of the liver. Butt and Wilder2 and Lawrence3 reported a longer survival period than this among their cases and predicted a reduction of the high mortality (50 per cent) noted by Sheldon1 due to diabetic coma. They felt that improved treatment of the associated
GRAY PA. HEMOCHROMATOSIS; A CASE REPORT WITH NECROPSY1. Ann Intern Med. ;19:501–506. doi: 10.7326/0003-4819-19-3-501
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Published: Ann Intern Med. 1943;19(3):501-506.
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