F. S. CHEEVER; B. B. BREESE; H. C. UPHAM
This paper deals with an investigation of the efficacy of sulfadiazine in clearing the nasopharynx of meningococci. Since the meningococcus carrier is generally considered to be the paramount factor in the spread of an epidemic of meningococcal meningitis, any therapeutic agent consistently successful in eliminating the specific organism from the posterior nasopharynx might well prove to be of considerable value in the prophylaxis of the disease. Various members of the sulfonamide group of drugs have given promising results. The original observations of Meehan and Merrilles1 on the successful use of sulfapyridine have been confirmed by others2, 3 and extended to
CHEEVER FS, BREESE BB, UPHAM HC. THE TREATMENT OF MENINGOCOCCUS CARRIERS WITH SULFADIAZINE1. Ann Intern Med. 1943;19:602–608. doi: 10.7326/0003-4819-19-4-602
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Published: Ann Intern Med. 1943;19(4):602-608.
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