The importance of the rôle of the venopressor mechanism in maintaining the circulation has become generally known in large part through the work of Henderson and his associates. Henderson1 has recently summarized his conceptions of this mechanism and the significance of its failure in the production of shock.
Maintenance of a normal circulation (i.e., a normal minute-volume output by the heart) depends not merely upon an effectively functioning myocardium but also upon the delivery through the veins to the right side of the heart of a quantity of blood sufficient to fill the cavities. There had long been difficulty in
FAILURE OF THE VENOPRESSOR MECHANISM AS A FACTOR IN THE DEVELOPMENT OF SHOCK. Ann Intern Med. ;19:817–819. doi: 10.7326/0003-4819-19-5-817
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Published: Ann Intern Med. 1943;19(5):817-819.
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