ROBERT J. KOSITCHEK, M.D.
The purpose of this paper is to present a case of monocytic leukemia which demonstrates the bone involvement previously observed in the lymphocytic and myelogenous types of leukemia. A review of the literature has failed to reveal similar bone involvement in leukemias in which the dominant cell is a monocyte or one of its immature forms.
Numerous accounts of bone changes in leukemia have appeared in the literature. In 1878, Newman and Eisenlohr5 described pathological changes in the bones in leukemia. Subsequent reports of bone changes in myelogenous and lymphatic leukemia were made by Osler,19 Snelling and Brown,23 Doub and
KOSITCHEK RJ. MONOCYTIC LEUKEMIA ASSOCIATED WITH BONE CHANGES1. Ann Intern Med. ;19:1008–1013. doi: 10.7326/0003-4819-19-6-1008
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Published: Ann Intern Med. 1943;19(6):1008-1013.
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