IRVING LEINWAND, M.D.; A. WILBUR DURYEE, M.D., F.A.C.P.
In 1926 M. Labbé and P. Renault1 observed a case of "hypertrophic osteo-dermopathology." In 1927 Gronberg2 described the syndrome "Magalia cutis et osseum." He collected nine similar cases from the literature in the preceding 16 years. In 1935, Touraine, Solente and Golé3 designated and described "un syndrome osteo-dermapathique." This syndrome is characterized by lesions of thickened skin with furrowing of the scalp, forehead, face, and extremities associated with elephantiasis of the long bones without involvement of the joints. They reported several cases which had been previously classified as dermatological, associated with a pulmonary osteoarthropathy. These skin lesions were usually diagnosed
LEINWAND I, DURYEE AW. CHRONIC HYPERTROPHY OF THE SKIN AND LONG BONES: AN OSTEO-DERMOPATHIC SYNDROME(CHRONIC HYPERTROPHY OF THE SKIN AND LONG BONES: AN OSTEO-DERMOPATHIC SYNDROME*). Ann Intern Med. 1943;19:1018–1028. doi: 10.7326/0003-4819-19-6-1018
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Published: Ann Intern Med. 1943;19(6):1018-1028.
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