M. A. BLANKENHORN, F.A.C.P.
Multiple peripheral neuritis occurring with sulfonamide therapy may become an important consideration as such therapy is extended and as the drugs are used prolongedly in infections. The incidence of such neuritis at present is difficult to ascertain. Only isolated cases are reported. It is said that the complication is rare and that it may follow prolonged use and large dosage.1
During the treatment of approximately 627 patients on the medical service of the Cincinnati General Hospital in 1942, peripheral neuritis occurred in six instances in which sulfonamides must be considered as a possible cause.
Multiple peripheral neuritis is not a
BLANKENHORN MA. MULTIPLE PERIPHERAL NEURITIS OCCURRING WITH SULFONAMIDE THERAPY1. Ann Intern Med. ;20:423–430. doi: 10.7326/0003-4819-20-3-423
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Published: Ann Intern Med. 1944;20(3):423-430.
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