CHARLES S. HIGLEY, M.D., F.A.C.P.
The circulating blood of normal adults rarely contains nucleated members of the erythrocyte series. The megaloblast, erythroblast, pronormoblast and normoblast are normally retained in the bone marrow until fully matured before released.
In certain diseases, however, the immature forms may make their appearance in the circulation. The megaloblast occasionally is found in myelogenous leukemia, macrocytic anemias, lead poisoning, or other anemias associated with rapid cell formation.1 The erythroblast may be found in the blood of normal new born infants during the first five days of life and is also found in the same diseases enumerated for the megaloblast.1 Pronormoblasts may
HIGLEY CS. ERYTHROBLASTIC ANEMIA OF THE ADULT1. Ann Intern Med. ;20:527–534. doi: 10.7326/0003-4819-20-3-527
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Published: Ann Intern Med. 1944;20(3):527-534.
Hematology/Oncology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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