ROY R. KRACKE, M.D.; WILLIAM R. PLATT, M.D.
In 1940, Landsteiner and Wiener1 discovered the existence of a new blood group factor in man following the injection of rabbits with the blood of the Macacus rhesus monkey. The serum of the immunized rabbits clumped not only the blood cells of the Rhesus monkeys but also the blood of about 85 per cent of human beings irrespective of their blood groups, thus revealing the presence in man of a new blood factor designated as Rh, because it was first found in the Rhesus monkey.
Present knowledge of the Rh factor can be summarized as follows2: (a) it is an
KRACKE RR, PLATT WR. THE CLINICAL SIGNIFICANCE OF THE Rh FACTOR WITH COMMENTS CONCERNING THE LABORATORY PROBLEMS(THE CLINICAL SIGNIFICANCE OF THE Rh FACTOR WITH COMMENTS CONCERNING THE LABORATORY PROBLEMS*). Ann Intern Med. 1944;20:559–569. doi: 10.7326/0003-4819-20-4-559
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Published: Ann Intern Med. 1944;20(4):559-569.
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