IRVING M. ARIEL, M.D.; JULES C. ABELS, M.D.; HELEN T. MURPHY, PH.D.; GEORGE T. PACK, M.D.; C. P. RHOADS, M.D., F.A.C.P.
Previous studies from this hospital have demonstrated that patients with gastrointestinal cancer frequently have several abnormalities of hepatic function.1, 2 The existence of these disorders appears to be due to the presence of the neoplasm, for when it is removed the functional capacity of the liver improves.2 The occurrence of hepatic insufficiency in these patients seldom has been found to be associated with those morphological alterations of the liver3 commonly observed in patients who suffer from chronic alcoholism or cirrhosis.4
The possibility existed that even though the livers of patients with gastrointestinal tract cancer were morphologically intact, their chemical
ARIEL IM, ABELS JC, MURPHY HT, PACK GT, RHOADS CP. METABOLIC STUDIES IN PATIENTS WITH CANCER OF THE GASTROINTESTINAL TRACT. VIII. THE CHEMICAL COMPOSITION OF THE LIVER, ESPECIALLY IN PATIENTS WITH GASTROINTESTINAL CANCER1. Ann Intern Med. ;20:570–579. doi: 10.7326/0003-4819-20-4-570
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Published: Ann Intern Med. 1944;20(4):570-579.
Gastroenterology/Hepatology, Gastrointestinal Cancer, Hematology/Oncology, Liver Disease.
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