N. E. ROSSETT, M.D.; JAMES FLEXNER, M.D.
In a previous communication1 we described a method for the continuous recording of gastric pH in man. At that time we were of the opinion that colloidal aluminum hydroxide2 in 30 c.c. dosage made up to 200 c.c. with water, or 200 c.c. of milk alone, fulfilled the physiological criteria of an ideal antacid. It was also noted that the use of calcium carbonate or of magnesium salts caused a great initial rise in pH but that their buffering effect was of short duration.
In the present study we have extended our observations on antacids with the use of an
ROSSETT NE, FLEXNER J. THE EFFECT OF CERTAIN ANTACIDS IN MAN MEASURED BY A SIMPLIFIED METHOD FOR THE CONTINUOUS RECORDING OF GASTRIC pH1. Ann Intern Med. ;21:119–121. doi: 10.7326/0003-4819-21-1-119
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Published: Ann Intern Med. 1944;21(1):119-121.
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