JOHN MARTIN ASKEY, M.D., F.A.C.P.
Addisonian pernicious anemia is known to develop in accordance with genetic, racial, climatic and geographic determinants. The hypothesis that the disease is of dietary origin has been advanced. If dietary deficiencies cause Addisonian pernicious anemia, they must explain the natural distribution and the natural history of the typical form of the disease.
The Natural Distribution of the Disease. Pernicious anemia is geographically distributed. It is rare in Asia, common in Northern Europe, Canada and the Northern United States. It is less common in the Mediterranean and Southern European areas, in South America and Southern United States.
Racially, it is extremely
ASKEY JM. THE DIETARY FACTOR IN THE ETIOLOGY OF PERNICIOUS ANEMIA1. Ann Intern Med. 1944;21:402–411. doi: 10.7326/0003-4819-21-3-402
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Published: Ann Intern Med. 1944;21(3):402-411.
Hematology/Oncology, Red Cell Disorders.
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