DANIEL B. FAUST, M.D., F.A.C.P.; HUGH R. GILMORE JR., M.D., F.A.C.P.; CHARLES S. MUDGETT, M.D., F.A.C.P.
Chordomata are tumors that arise from remnants of the fetal notochord. These remnants may be situated in any of the intervertebral discs and in the region of the spheno-occipital or sacro-coccygeal articulations. They rarely occur in the mandible or maxilla. These notochordal remnants frequently give rise to small tumors termed ecchordosis physaliphora by Luschka1 in 1856, and by Virchow2 in 1857. Virchow considered these tumors to be of cartilaginous origin, but Ribbert,3 supported by Müller's4 theory, believed that they arose from remnants of notochordal tissue. Ribbert noted the resemblance of the cells to those of the notochord, and furthermore
FAUST DB, GILMORE HR, MUDGETT CS. CHORDOMATA: A REVIEW OF THE LITERATURE, WITH REPORT OF A SACROCOCCYGEAL CASE1. Ann Intern Med. 1944;21:678–698. doi: 10.7326/0003-4819-21-4-678
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Published: Ann Intern Med. 1944;21(4):678-698.
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