HENRY B. SUTTON, M.D., F.A.C.S.; NORMAN S. MOORE, M.D., F.A.C.P.
Congenital hemolytic jaundice is a chronic blood dyscrasia generally characterized by microcytic anemia, acholuric jaundice, increased fragility of the red blood corpuscles to hypotonic salt solution, reticulocytosis, splenomegaly, and crises of hemolysis. It has frequently been stated that the victims are more jaundiced than ill. The belief that it follows a benign course, compatible with active and long life except when hemolytic crisis occurs, has been widely accepted. Many cases, however, do not follow this benign pattern.1, 2, 3, 4, 25, 33, 36, 38 There is an increasing disposition to emphasize the more severe aspects of this disease1, 2, 5,
SUTTON HB, MOORE NS. THE DIAGNOSIS AND TREATMENT OF CONGENITAL HEMOLYTIC (SPHEROCYTIC) JAUNDICE: REPORT OF A CASE WITH UNUSUAL BLOOD FINDINGS ALTERED BY LIVER THERAPY1. Ann Intern Med. 1944;21:698–708. doi: 10.7326/0003-4819-21-4-698
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Published: Ann Intern Med. 1944;21(4):698-708.
Gastroenterology/Hepatology, Liver Disease.
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