Although salicylates have been used in the treatment of rheumatic fever for nearly seventy years, there is still a wide divergence of opinion as to the degree of their effectiveness. There is no doubt as to their ability, even in moderate doses (up to six grams a day), to relieve the pains of arthritis, to alleviate the local manifestations of inflammation in the joints and usually to control the fever, at least temporarily. There is also general agreement that they do not exert a direct destructive action on the infectious agent. There is more difference of opinion as to their
SALICYLATES IN THE TREATMENT OF RHEUMATIC FEVER. Ann Intern Med. ;21:718–721. doi: 10.7326/0003-4819-21-4-718
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Published: Ann Intern Med. 1944;21(4):718-721.
Infectious Disease, Rheumatology, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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