SAUL R. KELSON
Analysis of 250 well-authenticated cases of subacute bacterial (streptococcal) endocarditis studied during the years from 1927 to 1939 disclosed the ineffectiveness of all methods of therapy prior to the introduction of the sulfonamide drugs.1 Sulfanilamide and particularly sulfapyridine appeared favorably to influence the course of the infection; in some instances, reduced fever and negative blood cultures temporarily followed the use of these drugs. Subsequent experience in the treatment of this disease has made clearer the effects of sulfanilamide and its derivatives, which are shown in the following summary. Some of the cases treated with sulfanilamide and sulfapyridine were collected from
KELSON SR. OBSERVATIONS ON THE TREATMENT OF SUBACUTE BACTERIAL (STREPTOCOCCAL) ENDOCARDITIS SINCE 19391. Ann Intern Med. ;22:75–96. doi: 10.7326/0003-4819-22-1-75
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Published: Ann Intern Med. 1945;22(1):75-96.
Cardiology, Endocarditis, Infectious Disease, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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