C. F. KEMPER, M.D., F.A.C.P.
The implantation of normal suprarenal glands or a potent extract of normal suprarenal glands has been foreshadowed since Addison's disease was first put on a sound clinicopathological basis in 1855. At that time, in his search for an explanation of idiopathic anemia, Thomas Addison as he said "stumbled upon the curious facts" that some asthenic patients of "dingy hue" were found at postmortem examination to have but one demonstrable pathological lesion and that was the destruction of the suprarenal capsules. Obviously he concluded that some significant relationship exists between the clinical syndrome and the pathological changes which he had so
KEMPER CF. THE TREATMENT OF ADDISON'S DISEASE BY THE IMPLANTATION METHOD1. Ann Intern Med. ;22:161–169. doi: 10.7326/0003-4819-22-2-161
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Published: Ann Intern Med. 1945;22(2):161-169.
Adrenal Disorders, Endocrine and Metabolism.
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