The problems concerned with the formation of antibodies have stimulated the interest of investigators for many years. One of the most interesting of these concerns the site of antibody formation and the types of cells concerned in the process. Is this a general property of all or most of the cells of the body, or is it restricted to certain special types of cells? In spite of a great deal of speculation and study, relatively little direct evidence in answer to these questions has been obtained.
Since the observations of Metschnikoff and his followers over 50 years ago, attention has
THE SITE OF ANTIBODY FORMATION. Ann Intern Med. ;22:295–298. doi: 10.7326/0003-4819-22-2-295
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Published: Ann Intern Med. 1945;22(2):295-298.
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