IRVING I. GOODOF, M.D.
In 1936, Kimmelstiel and Wilson1 first described a pathologic change in the kidneys which they called intercapillary glomerulosclerosis. Of their eight cases, seven were known to have had diabetes mellitus. Since that time there have been several conflicting reports regarding the incidence and nature of this lesion. This study was undertaken in an attempt to correlate the glomerular changes with various clinical and anatomic findings in the hope that some light may be thrown on the pathogenesis and significance of the lesion.
In the eight instances of intercapillary glomerulosclerosis reported by Kimmelstiel and Wilson, diabetes mellitus, hypertension, albuminuria, and edema
GOODOF II. INTERCAPILLARY GLOMERULOSCLEROSIS1. Ann Intern Med. ;22:373–381. doi: 10.7326/0003-4819-22-3-373
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Published: Ann Intern Med. 1945;22(3):373-381.
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