ALBERT I. MENDELOFF, M.D.
It is common knowledge today that respiratory symptoms are not infrequent manifestations of malignant disease arising elsewhere than in the lungs. Metastases to the lung are of fairly common occurrence in a great variety of carcinomata; these metastases usually occur as nodular, solid, or linear masses, without constant relationship to lymphatics, arterioles, or venules. Less commonly, the neoplastic cells are found almost exclusively within the pulmonary lymphatics, and may in addition permeate the venules or arterioles. This type of "carcinomatous lymphangitis" was first described by Andral,1 mentioned again by Virchow,2 and more fully elaborated by Troisier.3 The frequency with which
MENDELOFF AI. SEVERE ASTHMATIC DYSPNEA AS THE SOLE PRESENTING SYMPTOM OF GENERALIZED ENDOLYMPHATIC CARCINOMATOSIS: REPORT OF TWO CASES WITH AUTOPSY FINDINGS AND REVIEW OF THE PERTINENT LITERATURE1. Ann Intern Med. ;22:386–397. doi: 10.7326/0003-4819-22-3-386
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Published: Ann Intern Med. 1945;22(3):386-397.
Asthma, Pulmonary/Critical Care.
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