JAMES E. PAULLIN, M.D., F.A.C.P.; CHRISTOPHER JOHN MCLOUGHLIN, M.D.
The results of treatment of subacute bacterial endocarditis have been as disappointing and unavailing as of any disease known to medicine. The disease is not uncommon and is found most frequently in localities where rheumatic heart disease is common. Until the present time treatment has been discouraging; attempts to immunize the patient by vaccines, serums, and non-specific shock therapies were very disappointing; in fact these methods seemed to shorten the patient's life rather than prolong it. Intravenous injections of mercurochrome, acriflavine, and gentian violet produced no results, although some of them were encouraging, particularly the use of merthiolate which seemed
PAULLIN JE, MCLOUGHLIN CJ. THE TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITIS WITH PENICILLIN1. Ann Intern Med. ;22:475–484. doi: 10.7326/0003-4819-22-4-475
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Published: Ann Intern Med. 1945;22(4):475-484.
Cardiology, Endocarditis, Infectious Disease, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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