ALVAN L. BARACH, M.D., F.A.C.P.; FREDERICK H. SILBERSTEIN, M.D.; ENID TRIBE OPPENHEIMER, B.S.; THOMAS HUNTER, M.D.; MAX SOROKA, B.S.
The purpose of this communication is to present the results of an exploratory study on the technic, safety and clinical effectiveness of inhaling penicillin aerosol in patients with bronchopulmonary infection. Many questions concerning dosage of the drug, length of treatment and choice of apparatus require further investigation. Our preliminary findings are reported in order that other workers in this field may study this relatively simple method of local application of penicillin to the bronchi and lung parenchyma, since the response in some patients has been of an encouraging nature. That penicillin aerosol penetrates the lungs and may be recovered from
BARACH AL, SILBERSTEIN FH, OPPENHEIMER ET, HUNTER T, SOROKA M. INHALATION OF PENICILLIN AEROSOL IN PATIENTS WITH BRONCHIAL ASTHMA, CHRONIC BRONCHITIS, BRONCHIECTASIS AND LUNG ABSCESS: PRELIMINARY REPORT(INHALATION OF PENICILLIN AEROSOL IN PATIENTS WITH BRONCHIAL ASTHMA, CHRONIC BRONCHITIS, BRONCHIECTASIS AND LUNG ABSCESS: PRELIMINARY REPORT*). Ann Intern Med. 1945;22:485–509. doi: 10.7326/0003-4819-22-4-485
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Published: Ann Intern Med. 1945;22(4):485-509.
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