HAROLD J. F. KULLMAN; JACOB ANTRIM CRELLIN
Since penicillin has been employed clinically only since 1941 and, until comparatively recently, has not been available in sufficient quantity to permit the study of a large series of cases, the amount of literature concerning its clinical use in suppurative diseases of the lungs is necessarily limited. There is now sufficient evidence, however, to justify its employment in pneumonia, suppurative pneumonitis, lung abscess and empyema when due to an organism or organisms susceptible to the antibiotic action of penicillin.
Although a definite decrease of empyema has occurred since the use of the sulfonamides, there is a limited group of sulfonamide
KULLMAN HJF, CRELLIN JA. PENICILLIN IN SUPPURATIVE DISEASE OF THE LUNGS DUE TO STREPTOCOCCUS HEMOLYTICUS1. Ann Intern Med. ;23:135–146. doi: 10.7326/0003-4819-23-2-135
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Published: Ann Intern Med. 1945;23(2):135-146.
Infectious Disease, Pulmonary/Critical Care, Streptococcal Infections.
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