S. BEN-ASHER, M.D.
Of the numerous experimental investigations as to the pathogenesis of essential hypertension, the work of Goldblatt1 is beyond doubt the most outstanding. In a classical experiment he produced hypertension in the dog by constriction of one or both renal arteries with a silver clamp, with a resultant decrease in the blood flow through the kidney. These experiments have been repeated by other investigators with the same result. It is believed that the diminution in renal flow produces hypertension by the secretion of a pressor substance into the blood by the ischemic kidney. Since then a number of reports have appeared
BEN-ASHER S. HYPERTENSION CAUSED BY RENAL INFARCTION1. Ann Intern Med. ;23:431–436. doi: 10.7326/0003-4819-23-3-431
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Published: Ann Intern Med. 1945;23(3):431-436.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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