S. J. THANNHAUSER
Observations on these rare and apparently heredofamilial disorders are scattered throughout the different branches of medical literature according to the particular interest of the individual author specializing in involvement of the eye or the skin or the nervous system.
B. S. Oppenheimer and V. S. Kugel (1934) have the distinction of first reporting this condition in American medical literature, renaming it "Werner's syndrome." The characteristics of this syndrome are:
Shortness of stature, characteristic habitus
Canities (i.e., premature graying of the hair)
Trophic ulcers of the legs
Tendency to diabetes
Calcification of the blood vessels
THANNHAUSER SJ. WERNER'S SYNDROME (PROGERIA OF THE ADULT) AND ROTHMUND'S SYNDROME: TWO TYPES OF CLOSELY RELATED HEREDOFAMILIAL ATROPHIC DERMATOSES WITH JUVENILE CATARACTS AND ENDOCRINE FEATURES; A CRITICAL STUDY WITH FIVE NEW CASES1. Ann Intern Med. ;23:559–626. doi: 10.7326/0003-4819-23-4-559
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Published: Ann Intern Med. 1945;23(4):559-626.
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