MARTIN HENRY DAWSON, M.D.; THOMAS H. HUNTER, M.D.
In a recent communication1 the authors reported on the use of penicillin in the treatment of subacute bacterial endocarditis. Of 20 patients in whom the infecting agent was a streptococcus sensitive to the action of the drug, 15 apparently recovered; two were rendered free of infection as long as therapy was continued but subsequently relapsed; three succumbed. In the majority of cases, heparin was employed as an adjuvant to penicillin, but it was felt that further experience was necessary before an opinion could be expressed as to the value of this form of anticoagulant therapy. It was also realized that
DAWSON MH, HUNTER TH. THE TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITIS WITH PENICILLIN: SECOND REPORT1. Ann Intern Med. ;24:170–185. doi: 10.7326/0003-4819-24-2-170
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Published: Ann Intern Med. 1946;24(2):170-185.
Cardiology, Endocarditis, Infectious Disease, Streptococcal Infections.
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