GEORGE A. PERERA, M.D.
It has been previously observed that the increase in plasma volume, frequently encountered in patients with cardiac insufficiency, appears to be associated with right-sided failure.1 The suggestion that this may be due to dilatation of the portal circulatory bed in response to elevation of the venous pressure has led to the present study. In order to determine a possible relationship between portal hypertension and the plasma volume, measurements were made in a group of patients with cirrhosis of the liver.
Ten patients with Laennec's cirrhosis were studied on the wards of the Presbyterian Hospital. The clinical diagnosis
PERERA GA. THE PLASMA VOLUME IN LAENNEC'S CIRRHOSIS OF THE LIVER1. Ann Intern Med. ;24:643–647. doi: 10.7326/0003-4819-24-4-643
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Published: Ann Intern Med. 1946;24(4):643-647.
Gastroenterology/Hepatology, Liver Disease.
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