LAWRENCE I. KAPLAN; HILTON S. READ; DEWITT F. MULLINS
The rarity of spontaneous rupture of the spleen in naturally acquired malarial infections has been expressed by Manson-Bahr,1 Stitt,2 and Osler.3 Since the introduction of malaria as a therapeutic agent in the management of neurosyphilis, 31 cases of splenic rupture during treatment have been reported in the literature, either in detail or as personal references. Since this total cannot include unreported cases and cases that have not been recognized, the incidence of the complication probably approaches at least twice that number. Only one known case of recovery has followed splenectomy.4 In view of the gravity and unpredictability of this almost
KAPLAN LI, READ HS, MULLINS DF. SPONTANEOUS RUPTURE OF THE SPLEEN DURING MALARIA THERAPY; REPORT OF A CASE(SPONTANEOUS RUPTURE OF THE SPLEEN DURING MALARIA THERAPY; REPORT OF A CASE*). Ann Intern Med. 1946;24:707–714. doi: 10.7326/0003-4819-24-4-707
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Published: Ann Intern Med. 1946;24(4):707-714.
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