WILLIAM H. WOOD JR.; HENRY FELSON
Lymphogranuloma venereum is no longer thought of as a local infection of the genitalia, regional lymphatics, rectum, and sigmoid, but as Harrop1 has described, a systemic infection capable of producing headache, septic fever, chills, sweats, and articular rheumatism, and capable of involving lymphatics other than those of the inguinal and pelvic regions. The patient reacts to this infection with an elevation of serum globulin, thought by Schamberg2 to be an evidence of humoral antibody response. The skin becomes hypersensitive to the intradermal injection of suspensions of the inactivated virus, the Frei test.
Rake and his coworkers3 have improved the Frei
WOOD WH, FELSON H. A CASE OF LYMPHOGRANULOMA VENEREUM ASSOCIATED WITH ATYPICAL PNEUMONIA1. Ann Intern Med. 1946;24:904–908. doi: 10.7326/0003-4819-24-5-904
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Published: Ann Intern Med. 1946;24(5):904-908.
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