GEORGE D. GAMMON, M.D., F.A.C.P.; JOHN H. STOKES, M.D.; HOWARD P. STEIGER; WILLARD H. STEELE, M.D.; HERMAN BEERMAN, M.D.; NORMAN R. INGRAHAM JR., M.D.; PAUL GYORGY, M.D.; ELIZABETH ROSE, M.D.; JOHN W. LENTZ, M.D.; ABRAHAM ORNSTEEN, M.D., F.A.C.P.; DONALD SCOTT, M.D.
When we began the treatment of neurosyphilis with penicillin in November 1943, we determined to use penicillin alone without fever or arsenic or any other therapy which could influence the course of the disease. This seemed the obvious way to find out what the drug could accomplish, and we have followed this plan with a few exceptions which are noted. In substituting a new régime for the older routines of arsenicals and fever, we felt an urgent obligation to keep a close check on clinical effects as well as the results of blood and spinal fluid reactions. Furthermore, by carefully
GAMMON GD, STOKES JH, STEIGER HP, STEELE WH, BEERMAN H, INGRAHAM NR, et al. PENICILLIN THERAPY ALONE IN NEUROSYPHILIS: AN ANALYSIS OF CLINICAL RESULTS1. Ann Intern Med. ;25:412–432. doi: 10.7326/0003-4819-25-3-412
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Published: Ann Intern Med. 1946;25(3):412-432.
Infectious Disease, Sexually Transmitted Infections.
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