S. S. LICHTMAN, M.D., F.A.C.P.
Exposure to exotic diseases and infectious hepatitis of members of the armed forces necessitates reëvaluation of concepts of hepatic insufficiency by physicians. Recognition of relative hepatic insufficiency is not on a par with the diagnosis of insufficiency in other organs, and many physicians do not concern themselves with the liver until overt jaundice appears. Sensitive biochemical methods reveal that impaired liver function is far more common than previously suspected. The immense recuperative power of the liver masks the insufficiency until the parenchyma fails to eliminate bilirubin.
Mass wartime experience has firmly established the clinical and biochemical attributes of hepatic insufficiency
LICHTMAN SS. HEPATIC INSUFFICIENCY. I. PATHOPHYSIOLOGY AND CLINICAL ASPECTS1. Ann Intern Med. ;25:453–465. doi: 10.7326/0003-4819-25-3-453
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Published: Ann Intern Med. 1946;25(3):453-465.
Gastroenterology/Hepatology, Liver Disease.
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