SOL LEVY, M.D.; ROBERT J. KLEIN, M.D.
Porphyrins are chemical compounds participating in the normal pigment metabolism and occurring throughout the plant and animal worlds. They are of special interest in medicine because of their occurrence in hemoglobin, in bile-pigments, in chlorophyll, and in the widely distributed coloring matter, cytochrome. All porphyrins have a common chemical structure, namely four pyrrole rings bound by four additional carbon atoms, and are able to form compounds with metals. In the blood pigment the porphyrin is called protoporphyrin and this combined with iron and the protein fraction, globin, forms the basis for hemoglobin.
The organism receives the porphyrin either directly or
LEVY S, KLEIN RJ. HEMATOPORPHYRINURIA: REVIEW OF LITERATURE AND REPORT OF A CASE OF CHRONIC TYPE1. Ann Intern Med. 1946;25:520–525. doi: 10.7326/0003-4819-25-3-520
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Published: Ann Intern Med. 1946;25(3):520-525.
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