WALTER T. ZIMDAHL, B.A., M.D.
It has long been known that the magnesium ions act as a depressant to cardiac musculature. Smith, Winkler, and Hoff1 reported bradycardia, conduction disturbances and eventually cardiac arrest with high concentration resulting from parenteral administration. However, it was not until Boyd and Scherf2 reported their series of cases that the therapeutic effect and beneficial results of magnesium salts in paroxysmal tachycardia were generally recognized. The effect of intravenous injections of magnesium sulfate in 10 cases of paroxysmal tachycardia and one case of flutter was studied. They found that the injection of a 10 per cent solution was beneficial in three
ZIMDAHL WT. MAGNESIUM SULFATE IN PAROXYSMAL TACHYCARDIA1. Ann Intern Med. ;25:531–533. doi: 10.7326/0003-4819-25-3-531
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Published: Ann Intern Med. 1946;25(3):531-533.
Cardiology, Rhythm Disorders and Devices.
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