NORMAN REITMAN, M.D.
For many years it has been recognized that hemolytic streptococcus infections may cause secondary cardiac changes varying from endocarditis and subsequent valvular deformities to a diffuse pancarditis, or simply a transient involvement of the conduction system.
When there is an accompanying migratory polyarthritis, epistaxis, erythema marginatum or nodosum, or vague abdominal pain, the cardiac changes are said to be part of the symptom complex we recognize as rheumatic fever. However, when the pathologic change occurs in the conduction system alone, it is often difficult to prove that the cause is acute rheumatic fever; but on occasion the etiological agent causing
REITMAN N. THE ANTISTREPTOLYSIN TITER AS A DIAGNOSTIC AID IN CARDITIS OF OBSCURE ETIOLOGY1. Ann Intern Med. 1947;26:774–779. doi: 10.7326/0003-4819-26-5-774
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Published: Ann Intern Med. 1947;26(5):774-779.
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