H. M. MARGOLIS, M.D., F.A.C.P.; PAUL S. CAPLAN, M.D.
The value of therapy with gold salts in rheumatoid arthritis has been recognized increasingly as a useful addition to the therapeutic program in this disease. Unfortunately, toxic effects of varying degrees of severity have hindered wider employment of chrysotherapy and have often forced its discontinuance upon the appearance of the early signs of toxicity. The many types of toxic reactions resulting from chrysotherapy in rheumatoid arthritis will not be enumerated here since this subject has been discussed elsewhere.1
There has been a long felt need for some agent to counteract the toxic effects of gold therapy. Although various measures have
MARGOLIS HM, CAPLAN PS. BAL IN THE TREATMENT OF TOXICITY FROM GOLD1. Ann Intern Med. ;27:353–360. doi: 10.7326/0003-4819-27-3-353
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Published: Ann Intern Med. 1947;27(3):353-360.
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