SHERMAN M. MELLINKOFF; JOHN R. HIGGINS
Most textbooks state that the typical malaria patient exhibits chills, fever, and tachycardia.1, 2, 3, 4, 5 This clinical triad is frequently helpful in the differential diagnosis that runs through the physician's mind when he first sees a patient in a malarious zone. Among army personnel in certain regions of Asia, for example, it is common to see an acutely ill, prostrated man with chills and fever, while the physical examination gives no clue to the diagnosis except the heart rate. On the basis of probability in this particular locality, when there is a relative bradycardia one thinks of the
MELLINKOFF SM, HIGGINS JR. THE HEART RATE IN MALARIA; A REVIEW OF NINETY CASES1. Ann Intern Med. ;27:433–440. doi: 10.7326/0003-4819-27-3-433
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Published: Ann Intern Med. 1947;27(3):433-440.
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