L. W. GORHAM, M.D.; D. E. LESTER, M.D.; A. V. WOLF, Ph.D.; H. H. SHULTZ, M.D.
The restriction of sodium chloride intake has been recognized for many years as essential in the treatment of cardiac edema. A diminished renal excretion of sodium and water is the primary factor in the production of edema according to Warren and Stead,1 rather than increased venous pressure. Karrell's2 once popular regimen of 800 c.c. of milk with no other food or fluid contained approximately 1.0 gm. of sodium chloride. In many hospitals at the present time, the "cardiac general" diet restricts the sodium chloride intake to a minimum of 3.0 gm. and customarily fluids are limited to 1500 c.c. daily.
GORHAM LW, LESTER DE, WOLF AV, SHULTZ HH. THE RELATIVE IMPORTANCE OF DIETARY SODIUM CHLORIDE AND WATER INTAKE IN CARDIAC EDEMA1. Ann Intern Med. ;27:575–583. doi: 10.7326/0003-4819-27-4-575
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Published: Ann Intern Med. 1947;27(4):575-583.
Cardiology, Heart Failure.
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