GEORGE W. PEDIGO JR.; WILLIAM ABRAMSON
Hashimoto in 1912 described a clinical and pathological entity which consisted of diffuse enlargement of the thyroid in females with evidence of rich infiltration of the thyroid with connective tissue and lymphocytes and lymphoid hyperplasia. This condition not only has been called Hashimoto's disease but also struma lymphomatosa.
Since 1912 it has been debated as to whether this is a distinct clinical entity or a stage of Riedel's struma, as was suggested by Ewing1 in 1922. Several excellent reviews in the past few years indicate, however, that there is a distinction between struma lymphomatosa and Riedel's struma. Joll2 in 1939,
PEDIGO GW, ABRAMSON W. STRUMA LYMPHOMATOSA1. Ann Intern Med. ;27:627–632. doi: 10.7326/0003-4819-27-4-627
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Published: Ann Intern Med. 1947;27(4):627-632.
Endocrine and Metabolism, Thyroid Disorders.
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