A. C. CORCORAN; R. D. TAYLOR, F.A.C.P.; IRVINE H. PAGE, F.A.C.P.
The introduction of procedures by Homer Smith which permit the measurement of minimal renal blood and plasma flow, glomerular filtration rate and tubular secretory capacity has enabled measurement of renal function in terms which are functional rather than empirical. The validity of interpretations based on these methods is not seriously questioned when they are applied to the study of changes in the function of normal kidneys. Certain reservations need to be introduced in the presence of renal damage. Nevertheless, observation of changes of renal function and circulation in disease by these methods tends to reveal the nature and extent of
CORCORAN AC, TAYLOR RD, PAGE IH. FUNCTIONAL PATTERNS IN RENAL DISEASE1. Ann Intern Med. ;28:560–582. doi: 10.7326/0003-4819-28-3-560
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Published: Ann Intern Med. 1948;28(3):560-582.
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