C. WESLEY EISELE, M.D., F.A.C.P.; NORMAN B. MCCULLOUGH, Ph.D., M.D.; GRACE A. BEAL
Brucella agglutinins appearing after vaccination against cholera have been reported to occur in six of seven individuals.1 We have suggested that this phenomenon may be a source of confusion in the diagnosis of brucellosis inasmuch as the agglutination test is widely used for this purpose and several million veterans received cholera vaccine during their military service. The present studies were undertaken to determine further the effects of cholera vaccination on brucella agglutinin production and to observe the effects on the opsonocytophagic test and on the brucellergen skin test.
Twenty volunteers were selected who with one exception had
EISELE CW, MCCULLOUGH NB, BEAL GA. BRUCELLA ANTIBODIES FOLLOWING CHOLERA VACCINATION1. Ann Intern Med. ;28:833–837. doi: 10.7326/0003-4819-28-4-833
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Published: Ann Intern Med. 1948;28(4):833-837.
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