PAOLO RAVENNA, M.D.; JEROME SNYDER, M.D.
The symptoms and signs of infectious mononucleosis are variable and imitative of many common diseases. The diagnosis is made by the laboratory findings of a lymphocytosis with atypical cells and of an increased titer of the heterophile antibody (Paul-Bunnell test). Often these tests should be repeated, for a single negative result does not rule out the presence of the disease. Infectious mononucleosis should be suspected in every case of sore throat and in every acute illness with lymph node enlargement and/or splenomegaly, but unfortunately no single physical sign is so characteristic that its finding invites the repetition of the diagnostic
RAVENNA P, SNYDER J. THE OCCURRENCE OF EDEMA OF THE PHARYNX AND LARYNX IN INFECTIOUS MONONUCLEOSIS1. Ann Intern Med. 1948;28:861–866. doi: 10.7326/0003-4819-28-4-861
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Published: Ann Intern Med. 1948;28(4):861-866.
Infectious Disease, Pulmonary/Critical Care.
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