JANET W. MCARTHUR, M.D.; RULON W. RAWSON, M.D.; REX G. FLUHARTY; J. H. MEANS, M.D., F.A.C.P.
Thyrotoxicosis, in its classical form, is one of the most readily recognizable of all the diseases in medicine. In atypical form, however, hyperthyroidism may present formidable diagnostic difficulties. A growing number of laboratory aids have been devised to reduce the number of undiagnosed borderline cases, characterized by nervousness combined with a persistently elevated metabolic rate, which plague every thyroid clinic.
Among these auxiliary diagnostic technics is the so-called "iodine tolerance test," designed to appraise the functional activity of the thyroid gland by measurement of its capacity to take up iodine. Experimental precedent for this test derives from the classic perfusion
MCARTHUR JW, RAWSON RW, FLUHARTY RG, MEANS JH. THE URINARY EXCRETION OF RADIOACTIVE IODINE AS AN AID IN THE DIAGNOSIS OF HYPERTHYROIDISM1. Ann Intern Med. 1948;29:229–237. doi: 10.7326/0003-4819-29-2-229
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Published: Ann Intern Med. 1948;29(2):229-237.
Endocrine and Metabolism, Thyroid Disorders.
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