HARRY MARKOW, M.D.; MENDEL JACOBI, M.D., F.A.C.P.; HENRY RASCOFF, M.D., F.A.C.P.; BENJAMIN KOGUT, M.D.; ROMEO W. AUERBACH, M.D.
Gaseous oxygen has long been administered intravenously to animals without deleterious effects.1 Attempts have been made sporadically over many years to utilize the intravenous route for the administration of oxygen in cases of anoxia in man.2 These attempts were not continued further because of the development of such undesirable effects as embolism or cardiac tamponade. An analysis of these attempts shows that the amounts of oxygen administered were too large or that the gas was injected too rapidly or at too high a pressure. Ziegler,3 in 1941, described an apparatus for administering pure (commercial 100 per cent) oxygen intravenously at
MARKOW H, JACOBI M, RASCOFF H, KOGUT B, AUERBACH RW. EFFECT OF INTRAVENOUSLY ADMINISTERED OXYGEN ON SYMPTOMS AND VITAL CAPACITY IN BRONCHIAL ASTHMA1. Ann Intern Med. ;29:607–622. doi: 10.7326/0003-4819-29-4-607
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Published: Ann Intern Med. 1948;29(4):607-622.
Asthma, Pulmonary/Critical Care.
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