J. PHILIP LOGE, M.D.; EDWIN D. KILBOURNE, M.D.
During recent years the commonplace and ubiquitous entity of "streptococcus sore throat" has been the object of intensive study. Interest in hemolytic streptococcal pharyngitis has been heightened both by its importance as an acute epidemic disease during the war, and by its current recognition as a primary excitant of rheumatic fever and glomerulonephritis. Coincidentally, the discovery of effective antistreptococcal agents has aroused interest in the treatment of the acute disease and the prevention of its sequelae.
The critical appraisal of any treatment demands the establishment of strict control groups and accurate delineation of the natural history of the disease in
LOGE JP, KILBOURNE ED. PENICILLIN TREATMENT OF STREPTOCOCCAL PHARYNGITIS1. Ann Intern Med. ;29:698–714. doi: 10.7326/0003-4819-29-4-698
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Published: Ann Intern Med. 1948;29(4):698-714.
Infectious Disease, Streptococcal Infections.
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